Nowadays, mitochondrial dysfunctions are associated with a panel of pathologies such as cancer, diabetes, neurodegenerative diseases, migraine, infertility, kidney diseases, liver diseases, toxicity of HIV drugs, aging…
Mitochondria are ubiquitous organelles in eukaryotic cells whose primary function is to generate energy supplies in the form of ATP through oxidative phosphorylation. As a consequence, mitochondria produce Reactive Oxygen Species (ROS) and are highly vulnerable to oxidative damage. Moreover, mitochondria play a critical role in Ca2+ homeostasis, apoptosis, aging and development;bringing out mitochondria as an attractive target for drug and antioxidant-delivery strategies.
In this conference, different sessions will be held:
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- Mitochondrial dysfunctions in chronic diseases: recent advances and conclusions.
- Mitochondria in practice: methods and instruments.
- Strategies to target mitochondria.
- Targeting mitochondria: recent clinical and therapeutics studies.
Deadline for early registration and abstract submission for short oral presentation: 3 October 2010